Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24789418 | 0.88 | TMPRSS2 (0.35) | TMPRSS2TDP1 | |
| SCHEMBL24917272 | 0.88 | TMPRSS2 (0.43) | TMPRSS2TDP1 | |
| SCHEMBL24789734 | 0.87 | TMPRSS2 (0.42) | TMPRSS2TDP1HTR2CSLC6A4 | |
| SCHEMBL24917269 | 0.86 | TMPRSS2 (0.42) | TMPRSS2 | |
| SCHEMBL25913466 | 0.84 | TMPRSS2 (0.58) | TMPRSS2TDP1 | |
| SCHEMBL24917107 | 0.84 | TMPRSS2 (0.58) | TMPRSS2TDP1 | |
| SCHEMBL24916883 | 0.83 | POLRMT (0.33) | TMPRSS2 | |
| SCHEMBL25919712 | 0.82 | TMPRSS2 (0.45) | TMPRSS2 | |
| SCHEMBL24917295 | 0.81 | TMPRSS2 (0.35) | TMPRSS2 | |
| SCHEMBL24917317 | 0.78 | POLRMT (0.32) | TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230024722-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230024722-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | SLC29A2, SLC29A1, PNP | TMPRSS2 100/4885TDP1 874/4885HTR2C 1580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.