Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 4/20 | 0.38 |
| ▸ | SI | P14410 | 4/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.38 |
| ▸ | OGA | O60502 | 4/20 | 0.35 |
| ▸ | FGF1 | P05230 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18828872 | 0.86 | MGAM (0.38) | MGAMSILGALS8OGAFGF1 | |
| SCHEMBL19099658 | 0.83 | LGALS8 (0.41) | MGAMSILGALS8OGAALOX15 | |
| SCHEMBL8817524 | 0.83 | LGALS8 (0.41) | MGAMSILGALS8OGAALOX15 | |
| SCHEMBL26446515 | 0.83 | LGALS8 (0.41) | MGAMSILGALS8OGAALOX15 | |
| SCHEMBL7149469 | 0.83 | LGALS8 (0.41) | MGAMSILGALS8OGAALOX15 | |
| SCHEMBL8922707 | 0.83 | LGALS8 (0.41) | MGAMSILGALS8OGAALOX15 | |
| SCHEMBL8214723 | 0.83 | LGALS8 (0.41) | MGAMSILGALS8OGAALOX15 | |
| SCHEMBL8817519 | 0.83 | LGALS8 (0.41) | MGAMSILGALS8OGAALOX15 | |
| SCHEMBL21418786 | 0.83 | LGALS8 (0.41) | MGAMSILGALS8OGAALOX15 | |
| SCHEMBL7154677 | 0.83 | LGALS8 (0.41) | MGAMSILGALS8OGAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288033-A1 | ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |