⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25045619 | 0.68 | — | — | |
| SCHEMBL7998877 | 0.66 | MCHR1 (0.36) | — | |
| Ethane SCHEMBL1752493 | 0.64 | TGFBR1 (0.42) | — | |
| SCHEMBL19631265 | 0.64 | KDM4E (0.33) | — | |
| SCHEMBL4566859 | 0.63 | KDM4E (0.41) | — | |
| SCHEMBL20160365 | 0.62 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL15111001 | 0.62 | APP (0.33) | — | |
| SCHEMBL1500061 | 0.61 | MCHR1 (0.41) | — | |
| SCHEMBL25044246 | 0.60 | APP (0.30) | — | |
| SCHEMBL5579948 | 0.60 | MAPT (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004138-A1 | AGONISTS OF TYRO3 AS PROTECTION AGAINST PODOCYTE INJURY IN KIDNEY GLOMERULAR DISEASE | DAS BHASKAR (US) | 2023-01-26 | — | — | WO | disclosed |