Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17026631 | 0.87 | ESR1 (0.36) | KDM4EALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL17026547 | 0.84 | ELANE (0.42) | KDM4EALDH1A1LMNAHTTKMT2A | |
| SCHEMBL19236962 | 0.84 | MEN1 (0.41) | ALDH1A1SMN1; SMN2LMNAKMT2AMAPT | |
| SCHEMBL24920126 | 0.79 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL15541589 | 0.77 | HTR6 (0.39) | KDM4EALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL29781792 | 0.76 | BRD4 (0.37) | KDM4EALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL19208089 | 0.76 | BRD4 (0.37) | KDM4EALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL17026619 | 0.74 | HSD17B10 (0.43) | ALDH1A1LMNAESR1ELANEHSD17B10 | |
| SCHEMBL12480168 | 0.72 | MAPT (0.48) | KDM4EALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL15541769 | 0.70 | JAK2 (0.40) | KDM4EALDH1A1KMT2AMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11559515-B2 | Indole compounds and analogues thereof | BIOCRYST PHARMACEUTICALS, INC. (US) | 2023-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11559515-B2 | Indole compounds and analogues thereof | C5, IDO1, IDO2 | KDM4E 3768/4885ALDH1A1 1113/4885SMN1; SMN2 2964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.