Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 9/20 | 0.39 |
| ▸ | CA2 | P00918 | 9/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 6/20 | 0.38 |
| ▸ | CA9 | Q16790 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920230 | 1.00 | TDP1 (0.39) | TDP1CA1CA2MAOAMAOB | |
| SCHEMBL24920644 | 0.94 | ADORA1 (0.39) | TDP1CA1CA2MAOAMAOB | |
| SCHEMBL24920308 | 0.89 | TDP1 (0.48) | TDP1CA1CA2MAOAMAOB | |
| SCHEMBL24920288 | 0.86 | CA1 (0.34) | CA1CA2GAAPLK1 | |
| SCHEMBL26044735 | 0.84 | TDP1 (0.48) | TDP1CA1CA2MAOAMAOB | |
| SCHEMBL24686270 | 0.84 | TDP1 (0.43) | TDP1CA1CA2MAOAMAOB | |
| SCHEMBL24920229 | 0.84 | TDP1 (0.36) | TDP1CA1CA2MAOAMAOB | |
| SCHEMBL24920234 | 0.84 | TDP1 (0.36) | TDP1CA1CA2MAOAMAOB | |
| SCHEMBL16749961 | 0.84 | CA1 (0.39) | TDP1CA1CA2MAOAMAOB | |
| SCHEMBL16328105 | 0.83 | TDP1 (0.44) | TDP1CA1CA2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006782-A1 | CONJUGATING REAGENTS AND CONJUGATES THEREOF | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2023-02-02 | — | — | WO | disclosed |