Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 10/20 | 0.46 |
| ▸ | CA2 | P00918 | 10/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 6/20 | 0.44 |
| ▸ | CA9 | Q16790 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 2/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26044735 | 0.94 | TDP1 (0.48) | TDP1MAOAMAOBCA1CA2 | |
| SCHEMBL24686270 | 0.94 | TDP1 (0.43) | TDP1MAOAMAOBCA1CA2 | |
| SCHEMBL16328105 | 0.93 | TDP1 (0.44) | TDP1MAOAMAOBCA1CA2 | |
| SCHEMBL26032853 | 0.93 | TDP1 (0.42) | TDP1MAOAMAOBCA1CA2 | |
| SCHEMBL26032381 | 0.93 | TDP1 (0.42) | TDP1MAOAMAOBCA1CA2 | |
| SCHEMBL26046033 | 0.92 | TDP1 (0.46) | TDP1MAOAMAOBCA1CA2 | |
| SCHEMBL26045685 | 0.92 | TDP1 (0.46) | TDP1MAOAMAOBCA1CA2 | |
| SCHEMBL25835268 | 0.92 | TDP1 (0.43) | TDP1MAOAMAOBCA1CA2 | |
| SCHEMBL24920230 | 0.89 | TDP1 (0.39) | TDP1MAOAMAOBCA1CA2 | |
| SCHEMBL24920231 | 0.89 | TDP1 (0.39) | TDP1MAOAMAOBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006782-A1 | CONJUGATING REAGENTS AND CONJUGATES THEREOF | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2023-02-02 | — | — | WO | disclosed |