Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29512205 | 1.00 | ALDH1A1 (0.48) | ALDH1A1GAATSHRCYP3A4DPP4 | |
| SCHEMBL22042538 | 0.88 | ALDH1A1 (0.59) | ALDH1A1GAATSHRDPP4DPP8 | |
| SCHEMBL29512034 | 0.88 | ALDH1A1 (0.50) | ALDH1A1GAATSHRCYP3A4DPP4 | |
| SCHEMBL24226821 | 0.88 | ALDH1A1 (0.50) | ALDH1A1GAATSHRCYP3A4DPP4 | |
| SCHEMBL13469202 | 0.87 | ALDH1A1 (0.61) | ALDH1A1GAATSHRCYP3A4EPHX1 | |
| SCHEMBL24226839 | 0.82 | ALDH1A1 (0.55) | ALDH1A1GAATSHRCYP3A4EPHX1 | |
| SCHEMBL24226849 | 0.82 | ALDH1A1 (0.55) | ALDH1A1GAATSHRCYP3A4EPHX1 | |
| SCHEMBL16591256 | 0.82 | ALDH1A1 (0.58) | ALDH1A1GAATSHRDPP4DPP8 | |
| SCHEMBL16430947 | 0.82 | ALDH1A1 (0.58) | ALDH1A1GAATSHRDPP4DPP8 | |
| SCHEMBL24226881 | 0.81 | TSHR (0.55) | ALDH1A1GAATSHRCYP3A4DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230074669-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-03-09 | — | — | US | disclosed |
| US-20230030720-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230030720-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | MLLT1, MEN1, MLLT3 | ALDH1A1 3327/4885GAA 4877/4885TSHR 4729/4885 |
| US-20230074669-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | MLLT1, MEN1, MLLT3 | ALDH1A1 3327/4885GAA 4877/4885TSHR 4729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.