SCHEMBL24920331

SCHEMBL24920331

CC(C)(C)OC(=O)NCCOCCOCC(=O)NCCN(CCNC(=O)COCCOCCNC(=O)OC(C)(C)C)CC(=O)OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
IDO1 P14902 1/20 0.46
BCHE P06276 2/20 0.43
CNR2 P34972 2/20 0.43
SYK P43405 1/20 0.42
L3MBTL1 Q9Y468 3/20 0.40
MAPT P10636 2/20 0.40
GBA1 P04062 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CKS1B P61024 1/20 0.38
SKP1 P63208 1/20 0.38
SKP2 Q13309 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16995783 0.89 LMNA (0.52) LMNASMN1; SMN2IDO1BCHECNR2
SCHEMBL16995567 0.89 LMNA (0.52) LMNASMN1; SMN2IDO1BCHECNR2
SCHEMBL15516041 0.89 LMNA (0.56) LMNASMN1; SMN2IDO1BCHECNR2
SCHEMBL20107206 0.89 LMNA (0.56) LMNASMN1; SMN2IDO1BCHECNR2
SCHEMBL3830654 0.88 LMNA (0.55) LMNASMN1; SMN2IDO1BCHECNR2
SCHEMBL15515856 0.85 LMNA (0.52) LMNASMN1; SMN2IDO1BCHECNR2
SCHEMBL20107353 0.85 LMNA (0.61) LMNASMN1; SMN2IDO1BCHECNR2
SCHEMBL31041071 0.85 LMNA (0.51) LMNASMN1; SMN2IDO1BCHECNR2
SCHEMBL25463464 0.84 SYK (0.48) LMNASMN1; SMN2IDO1SYKL3MBTL1
SCHEMBL18429584 0.84 SYK (0.50) LMNASMN1; SMN2IDO1SYKL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023006782-A1 CONJUGATING REAGENTS AND CONJUGATES THEREOF CAMBRIDGE ENTERPRISE LIMITED (GB) 2023-02-02 WO disclosed