Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 8/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 10/20 | 0.42 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL643095 | 0.89 | AVPR1B (0.48) | AVPR1BAVPR1ABDKRB1HTR6MEN1 | |
| SCHEMBL645571 | 0.85 | AVPR1B (0.46) | AVPR1BAVPR1AMEN1KMT2A | |
| SCHEMBL642950 | 0.84 | AVPR1B (0.45) | AVPR1BAVPR1AMEN1KMT2A | |
| SCHEMBL493144 | 0.76 | BDKRB1 (0.40) | AVPR1BAVPR1ABDKRB1 | |
| SCHEMBL643968 | 0.76 | AVPR1B (0.43) | AVPR1BAVPR1ABDKRB1HTR6 | |
| SCHEMBL492675 | 0.76 | BDKRB1 (0.41) | AVPR1BAVPR1ABDKRB1 | |
| SCHEMBL493601 | 0.72 | AVPR1B (0.37) | AVPR1BAVPR1ABDKRB1HTR6 | |
| SCHEMBL492944 | 0.70 | BDKRB1 (0.42) | AVPR1ABDKRB1 | |
| SCHEMBL493207 | 0.70 | BDKRB1 (0.42) | AVPR1ABDKRB1 | |
| SCHEMBL493671 | 0.70 | BDKRB1 (0.41) | AVPR1BBDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150530-B1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2011-10-26 | — | — | EP | claimed |
| EP-2150530-B1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2011-10-26 | — | — | EP | disclosed |
| EP-2150530-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008131947-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2008-11-06 | — | — | WO | disclosed |