Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22350895 | 0.82 | — | — | |
| SCHEMBL21378809 | 0.79 | CTSD (0.39) | ALDH1A1TSHRTDP1MAPTLMNA | |
| SCHEMBL5692424 | 0.75 | TSHR (0.46) | ALDH1A1TSHRTDP1MAPTLMNA | |
| SCHEMBL23682391 | 0.74 | MCL1 (0.30) | MCL1LMNA | |
| SCHEMBL681118 | 0.74 | — | — | |
| SCHEMBL24567512 | 0.73 | SMN1; SMN2 (0.37) | ALDH1A1TSHRTDP1MAPTLMNA | |
| SCHEMBL557272 | 0.72 | — | — | |
| SCHEMBL4282052 | 0.72 | — | — | |
| SCHEMBL16092680 | 0.72 | HMGCR (0.50) | ALDH1A1TSHRMAPTMCL1LMNA | |
| SCHEMBL2792859 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |