Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9925951 | 0.83 | ALDH1A1 (0.46) | CYP2C19ALDH1A1LMNAHTTHSD17B10 | |
| SCHEMBL30922273 | 0.79 | CNR2 (0.47) | CYP2C19ALDH1A1LMNAHTTHSD17B10 | |
| SCHEMBL24921793 | 0.78 | ALDH1A1 (0.46) | CYP2C19ALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL18885167 | 0.77 | CYP11B1 (0.56) | CYP2C19ALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL10333903 | 0.77 | CYP2C19 (0.61) | CYP2C19ALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL24921465 | 0.76 | CYP2C19 (0.59) | CYP2C19ALDH1A1LMNAHTTHSD17B10 | |
| SCHEMBL807298 | 0.74 | ALDH1A1 (0.54) | CYP2C19ALDH1A1LMNAHTTHSD17B10 | |
| SCHEMBL19534370 | 0.74 | MTOR (0.39) | ALDH1A1LMNAHTTL3MBTL1HSD17B10 | |
| SCHEMBL24921115 | 0.74 | PIK3CD (0.44) | CYP2C19ALDH1A1LMNAHTTHSD17B10 | |
| SCHEMBL1271706 | 0.73 | ALDH1A1 (0.56) | CYP2C19ALDH1A1LMNAHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |