Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920886 | 0.90 | HSD11B1 (0.38) | NPC1RAB9ASMN1; SMN2GAACYP1A2 | |
| SCHEMBL24920736 | 0.85 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2GAACASP3 | |
| SCHEMBL24920722 | 0.84 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2GAACYP19A1 | |
| SCHEMBL24920726 | 0.84 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2GAACASP3 | |
| SCHEMBL24920735 | 0.84 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2GAACASP3 | |
| SCHEMBL24920733 | 0.84 | NPC1 (0.33) | NPC1RAB9ASMN1; SMN2GAACASP3 | |
| SCHEMBL24920745 | 0.83 | NPC1 (0.35) | NPC1RAB9ASMN1; SMN2GAACYP19A1 | |
| SCHEMBL24920742 | 0.83 | SMO (0.38) | NPC1RAB9ASMN1; SMN2GAACYP2C9 | |
| SCHEMBL24921636 | 0.81 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2GAACYP1A2 | |
| SCHEMBL24920723 | 0.81 | NPC1 (0.35) | NPC1RAB9ASMN1; SMN2GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |