SCHEMBL2492086

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2490782	0.83	CD274 (0.47)	CHRM2SCN8APDCD1LG2CD274ALDH1A1
	Diethylamine SCHEMBL6930279	0.82	HEXA (0.42)	CYP2D6TSHRHEXAHEXBALDH1A1
	SCHEMBL2491886	0.80	SCN8A (0.50)	CHRM2SCN8ACD274GAASLC6A4
	SCHEMBL23347216	0.78	SCN8A (0.43)	CHRM2SCN8ACD274GAASLC6A2
	SCHEMBL6659252	0.78	CHRM2 (0.62)	CHRM2GAASLC6A2SLC6A4SLC6A3
	SCHEMBL2494466	0.76	HTR1A (0.53)	CHRM2GAAMAPTTP53CYP2D6
	SCHEMBL11624233	0.75	HEXA (0.36)	CD274MAPTTSHRHEXAHEXB
	SCHEMBL19244144	0.74	GAA (0.46)	CHRM2SCN8APDCD1LG2CD274GAA
	Diethylamine SCHEMBL9189446	0.74	HEXA (0.45)	MAPTHSD17B10TP53MAPK1CYP2D6
	SCHEMBL21267257	0.72	CHRM2 (0.42)	CHRM2SCN8APDCD1LG2CD274GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.