Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24922741 | 0.98 | ALDH1A1 (0.38) | ALDH1A1GAAEPHX1HTR1BTSHR | |
| SCHEMBL24920408 | 0.95 | EPHX1 (0.44) | ALDH1A1GAAEPHX1HTR1BTSHR | |
| SCHEMBL24921956 | 0.93 | EPHX1 (0.42) | ALDH1A1GAAEPHX1HTR1BTSHR | |
| SCHEMBL24921934 | 0.93 | EPHX1 (0.42) | ALDH1A1GAAEPHX1HTR1BTSHR | |
| SCHEMBL24921948 | 0.93 | EPHX1 (0.42) | ALDH1A1GAAEPHX1HTR1BTSHR | |
| SCHEMBL24921938 | 0.93 | EPHX1 (0.42) | ALDH1A1GAAEPHX1HTR1BTSHR | |
| SCHEMBL24921955 | 0.93 | EPHX1 (0.42) | ALDH1A1GAAEPHX1HTR1BTSHR | |
| SCHEMBL24921947 | 0.93 | EPHX1 (0.42) | ALDH1A1GAAEPHX1HTR1BTSHR | |
| SCHEMBL24921935 | 0.93 | EPHX1 (0.42) | ALDH1A1GAAEPHX1HTR1BTSHR | |
| SCHEMBL24921840 | 0.93 | ALDH1A1 (0.40) | ALDH1A1GAAEPHX1HTR1BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |