Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.52 |
| ▸ | RIPK2 | O43353 | 4/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 7/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984470 | 0.82 | RIPK2 (0.46) | CYP11B1CYP11B2RIPK2CHRNB2CHRNA4 | |
| SCHEMBL24921580 | 0.81 | MAPKAPK2 (0.50) | — | |
| SCHEMBL19947421 | 0.81 | KDM4E (0.44) | CYP11B1CYP11B2RIPK2CHRNB2CHRNA4 | |
| SCHEMBL24921152 | 0.81 | NOTUM (0.50) | GRIN1GRIN2B | |
| SCHEMBL31014572 | 0.77 | RAB9A (0.46) | CYP11B1CYP11B2RIPK2CHRNB2CHRNA4 | |
| Bromide SCHEMBL31015249 | 0.76 | NPC1 (0.43) | CYP11B1CYP11B2RIPK2CHRNB2CHRNA4 | |
| SCHEMBL31015304 | 0.76 | CYP11B1 (0.43) | CYP11B1CYP11B2RIPK2CHRNB2CHRNA4 | |
| SCHEMBL31015139 | 0.76 | RIPK2 (0.49) | CYP11B1CYP11B2RIPK2 | |
| SCHEMBL31015116 | 0.75 | RIPK2 (0.51) | CYP11B1CYP11B2RIPK2 | |
| SCHEMBL30557250 | 0.75 | RIPK2 (0.39) | CYP11B2RIPK2CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |