Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 17/20 | 0.50 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1902668 | 1.00 | PTGDR2 (0.50) | PTGDR2HTR6CCR5 | |
| SCHEMBL2490281 | 0.91 | PTGDR2 (0.48) | PTGDR2HTR6CCR5 | |
| SCHEMBL1904071 | 0.91 | PTGDR2 (0.48) | PTGDR2HTR6CCR5 | |
| SCHEMBL1900791 | 0.91 | HTR6 (0.49) | PTGDR2HTR6 | |
| SCHEMBL2491106 | 0.91 | HTR6 (0.49) | PTGDR2HTR6 | |
| SCHEMBL2488598 | 0.90 | PTGDR2 (0.49) | PTGDR2HTR6 | |
| SCHEMBL2488596 | 0.90 | PTGDR2 (0.49) | PTGDR2HTR6 | |
| SCHEMBL1904643 | 0.86 | PTGDR2 (0.48) | PTGDR2HTR6 | |
| SCHEMBL2487579 | 0.86 | PTGDR2 (0.48) | PTGDR2HTR6 | |
| SCHEMBL1902660 | 0.85 | PTGDR2 (0.46) | PTGDR2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051962-B1 | (3-AMINO-1,2,3,4-TETRAHYDRO-9H-CARBAZOL-9-YL)-ACETIC ACID DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2011-10-26 | — | — | EP | disclosed |