Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL28190447 | 0.98 | TSHR (0.45) | TSHRSRD5A2KDM4EMEN1NPC1 | |
| SCHEMBL869560 | 0.84 | TAS1R3 (0.40) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL20934776 | 0.82 | SLC6A2 (0.43) | KDM4EMEN1NPC1MAPTRAB9A | |
| SCHEMBL31394687 | 0.82 | TSHR (0.42) | TSHRHSD17B10HPGDNPFFR2POLB | |
| SCHEMBL981100 | 0.82 | NPFFR2 (0.50) | NPFFR2 | |
| SCHEMBL27770756 | 0.82 | TSHR (0.44) | TSHRMAPTKMT2ANPFFR2 | |
| SCHEMBL113435 | 0.78 | HPGD (0.39) | TSHRHSD17B10HPGD | |
| SCHEMBL28800472 | 0.78 | AR (0.49) | — | |
| SCHEMBL570661 | 0.77 | — | — | |
| SCHEMBL14955984 | 0.77 | NOTUM (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782448-B1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS INC (US) | 2017-08-16 | — | — | EP | disclosed |
| EP-2782448-B1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS INC (US) | 2017-08-16 | — | — | EP | disclosed |
| US-20160000813-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. | 2016-01-07 | — | — | US | disclosed |
| US-20160000813-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. | 2016-01-07 | — | — | US | disclosed |
| US-20160000813-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. | 2016-01-07 | — | — | US | disclosed |
| US-9156860-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2015-10-13 | — | — | US | disclosed |
| US-9156860-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2015-10-13 | — | — | US | disclosed |
| US-9156860-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2015-10-13 | — | — | US | disclosed |
| US-20150025038-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. | 2015-01-22 | — | — | US | disclosed |
| US-20150025038-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. | 2015-01-22 | — | — | US | disclosed |
| US-8853186-B2 | Boron containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-8853186-B2 | Boron containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| EP-2782448-A1 | BORON-CONTAINING SMALL MOLECULES | Anacor Pharmaceuticals, Inc. (US) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013078070-A1 | BORON-CONTAINING SMALL MOLECULES | ELI LILLY AND COMPANY (US) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013078070-A1 | BORON-CONTAINING SMALL MOLECULES | ELI LILLY AND COMPANY (US) | 2013-05-30 | — | — | WO | disclosed |
| US-20130131016-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130131016-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130131016-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| EP-2379537-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010070068-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160000813-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, SLC7A5, BCL6 | TSHR 1108/4885SRD5A2 4242/4885KDM4E 2143/4885 |
| US-20130131016-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, SLC7A5, BCL6 | TSHR 1108/4885SRD5A2 4242/4885KDM4E 2143/4885 |
| US-20150025038-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, SLC7A5, BCL6 | TSHR 1108/4885SRD5A2 4242/4885KDM4E 2143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.