Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1905222 | 1.00 | OPRM1 (0.43) | OPRM1PTGDR2TMEM97PTGER2HTR6 | |
| SCHEMBL1905172 | 0.92 | PTGDR2 (0.44) | PTGDR2HTR6 | |
| SCHEMBL1905174 | 0.92 | PTGDR2 (0.44) | PTGDR2HTR6 | |
| SCHEMBL1902738 | 0.92 | PTGDR2 (0.40) | PTGDR2PTGER2HTR6 | |
| SCHEMBL1902739 | 0.92 | PTGDR2 (0.40) | PTGDR2PTGER2HTR6 | |
| SCHEMBL1901324 | 0.90 | PTGDR2 (0.44) | PTGDR2HTR6 | |
| SCHEMBL1901327 | 0.90 | PTGDR2 (0.44) | PTGDR2HTR6 | |
| SCHEMBL1901632 | 0.90 | PTGDR2 (0.47) | PTGDR2HTR6 | |
| SCHEMBL1901634 | 0.90 | PTGDR2 (0.47) | PTGDR2HTR6 | |
| SCHEMBL1900111 | 0.89 | PTGDR2 (0.42) | PTGDR2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051962-B1 | (3-AMINO-1,2,3,4-TETRAHYDRO-9H-CARBAZOL-9-YL)-ACETIC ACID DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2011-10-26 | — | — | EP | disclosed |