SCHEMBL2492349

SCHEMBL2492349

Oc1ccccc1/C=N\c1cccc(/N=C/c2ccccc2O)c1

nearest known ligand 0.74

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.74
CA2 P00918 8/20 0.62
CA9 Q16790 7/20 0.62
CA12 O43570 7/20 0.62
TSHR P16473 1/20 0.60
CA1 P00915 2/20 0.56
CA7 P43166 1/20 0.53
KDM4E B2RXH2 2/20 0.52
MAOB P27338 3/20 0.51
MAPT P10636 2/20 0.50
HSD17B10 Q99714 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
USP2 O75604 1/20 0.49
ALDH1A1 P00352 1/20 0.49
GAA P10253 1/20 0.49
ALOX15 P16050 1/20 0.49
ALOX12 P18054 1/20 0.49
HTT P42858 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2937662 1.00 SIRT2 (0.74) SIRT2CA2CA9CA12TSHR
SCHEMBL2492350 1.00 SIRT2 (0.74) SIRT2CA2CA9CA12TSHR
SCHEMBL11406841 0.91 SIRT2 (0.67) SIRT2CA2CA9CA12TSHR
SCHEMBL11406860 0.91 SIRT2 (0.67) SIRT2CA2CA9CA12TSHR
SCHEMBL11418959 0.88 SIRT2 (0.62) SIRT2CA2CA9CA12TSHR
SCHEMBL11404879 0.88 SIRT2 (0.62) SIRT2CA2CA9CA12TSHR
SCHEMBL1948751 0.88 SIRT2 (0.62) SIRT2CA2CA9CA12TSHR
SCHEMBL11418963 0.88 SIRT2 (0.62) SIRT2CA2CA9CA12TSHR
SCHEMBL1948748 0.88 SIRT2 (0.62) SIRT2CA2CA9CA12TSHR
SCHEMBL11404876 0.88 SIRT2 (0.62) SIRT2CA2CA9CA12TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8030382-B2 Polylactic acid composition TEIJIN LIMITED (JP) 2011-10-04 US disclosed
US-20100093888-A1 POLYLACTIC ACID COMPOSITION TEIJIN LIMITED (JP) 2010-04-15 US disclosed
EP-2116576-A1 POLYLACTIC ACID COMPOSITION Teijin Limited (JP) 2009-11-11 EP disclosed