Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 5/20 | 0.53 |
| ▸ | CA9 | Q16790 | 4/20 | 0.53 |
| ▸ | CA12 | O43570 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1948751 | 1.00 | SIRT2 (0.62) | SIRT2CA2CA9CA12TSHR | |
| SCHEMBL2492349 | 0.88 | SIRT2 (0.74) | SIRT2CA2CA9CA12TSHR | |
| SCHEMBL2937662 | 0.88 | SIRT2 (0.74) | SIRT2CA2CA9CA12TSHR | |
| SCHEMBL2492350 | 0.88 | SIRT2 (0.74) | SIRT2CA2CA9CA12TSHR | |
| SCHEMBL15347538 | 0.84 | MAPT (0.63) | CA2CA9CA12TSHRCA1 | |
| SCHEMBL15347537 | 0.84 | MAPT (0.63) | CA2CA9CA12TSHRCA1 | |
| SCHEMBL11406841 | 0.83 | SIRT2 (0.67) | SIRT2CA2CA9CA12TSHR | |
| SCHEMBL11406860 | 0.83 | SIRT2 (0.67) | SIRT2CA2CA9CA12TSHR | |
| SCHEMBL5784155 | 0.81 | SIRT2 (0.81) | SIRT2CA2CA9CA12TSHR | |
| SCHEMBL5784154 | 0.81 | SIRT2 (0.81) | SIRT2CA2CA9CA12TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2151446-B1 | Process for the preparation of bidentate schiff base ruthenium catalysts containing a salicylaldimine-type ligand | RIMTEC CORP (JP) | 2016-04-13 | — | — | EP | disclosed |
| EP-2151445-B1 | Process for the preparation of bidentate Schiff base ruthenium catalysts containing a salicylaldimine-type ligand | RIMTEC CORP (JP) | 2015-02-18 | — | — | EP | disclosed |
| US-8338613-B2 | Process for the preparation of bidentate schiff base ruthenium catalysts containing a salicylaldimine-type ligand | RIMTEC CORPORATION (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20110137043-A1 | Process for the preparation of bidentate schiff base ruthenium catalysts containing a salicylaldimine-type ligand | TELENE S.A.S. (FR) | 2011-06-09 | — | — | US | disclosed |
| US-20110065925-A1 | Process for the preparation of bidentate schiff base ruthenium catalysts containing a salicylaldimine-type ligand | TELENE S.A.S. (FR) | 2011-03-17 | — | — | US | disclosed |
| EP-2151446-A1 | Process for the preparation of bidentate schiff base ruthenium catalysts containing a salicylaldimine-type ligand | Telene SAS (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151445-A1 | Process for the preparation of bidentate Schiff base ruthenium cataysts containing a saliclyldimine-type ligand | Telene SAS (FR) | 2010-02-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110137043-A1 | Process for the preparation of bidentate schiff base ruthenium catalysts containing a salicylaldimine-type ligand | SPR, LIG4, SUCLA2 | SIRT2 135/4885CA2 1434/4885CA9 2120/4885 |
| US-20110065925-A1 | Process for the preparation of bidentate schiff base ruthenium catalysts containing a salicylaldimine-type ligand | SPR, LIG4, SUCLA2 | SIRT2 135/4885CA2 1434/4885CA9 2120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.