Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27593308 | 0.78 | CYP1A2 (0.47) | CYP1A2CYP2D6PGRADRA2AADRA2B | |
| SCHEMBL9850550 | 0.75 | PGR (0.46) | CYP1A2CYP2D6PGRADRA2AADRA2B | |
| SCHEMBL2201172 | 0.73 | CES1 (0.48) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL5819903 | 0.72 | CES1 (0.47) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL15658023 | 0.71 | PGR (0.48) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL19863258 | 0.70 | CES1 (0.45) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL27325598 | 0.70 | PGR (0.47) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL27988949 | 0.70 | PGR (0.47) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL19863241 | 0.69 | CES1 (0.44) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL3648188 | 0.67 | CES1 (0.50) | PGRADRA2AADRA2BHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10919938-B2 | Modified cyclopentapeptides and uses thereof | Technische Universität München (DE) | 2021-02-16 | — | — | US | disclosed |
| EP-3152226-B1 | MODIFIED CYCLOPENTAPEPTIDES AND USES THEREOF | UNIV MUENCHEN TECH (DE) | 2019-05-29 | — | — | EP | disclosed |
| US-20180037608-A1 | MODIFIED CYCLOPENTAPEPTIDES AND USES THEREOF | Technische Universität München (DE) | 2018-02-08 | — | — | US | disclosed |
| EP-3152226-A1 | MODIFIED CYCLOPENTAPEPTIDES AND USES THEREOF | Technische Universität München (DE) | 2017-04-12 | — | — | EP | disclosed |
| EP-2560690-B1 | CYCLOPENTAPEPTIDE DERIVATIVES AND USES THEREOF | Technische Universität München (DE) | 2017-03-08 | — | — | EP | disclosed |
| US-9266924-B2 | Cyclopentapeptide derivatives and uses thereof | Technische Universität München (DE) | 2016-02-23 | — | — | US | disclosed |
| WO-2015185162-A1 | MODIFIED CYCLOPENTAPEPTIDES AND USES THEREOF | Technische Universität München (DE) | 2015-12-10 | — | — | WO | disclosed |
| US-20130217871-A1 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-08-22 | — | — | US | disclosed |
| US-20130129622-A1 | CYCLOPENTAPEPTIDE DERIVATIVES AND USES THEREOF | Technische Universität München (DE) | 2013-05-23 | — | — | US | disclosed |
| EP-2560690-A1 | CYCLOPENTAPEPTIDE DERIVATIVES AND USES THEREOF | Technische Universität München (DE) | 2013-02-27 | — | — | EP | disclosed |
| WO-2011131731-A1 | CYCLOPEPTIDE DERIVATIVES AND USES THEREOF | Technische Universität München (DE) | 2011-10-27 | — | — | WO | disclosed |
| WO-2011131735-A1 | CYCLOPENTAPEPTIDE DERIVATIVES AND USES THEREOF | Technische Universität München (DE) | 2011-10-27 | — | — | WO | disclosed |
| EP-2380596-A1 | Cyclopentapeptide derivatives and uses thereof | Technische Universität München (DE) | 2011-10-26 | — | — | EP | disclosed |
| EP-2380597-A1 | Cyclopeptide derivatives and uses thereof | Technische Universität München (DE) | 2011-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037608-A1 | MODIFIED CYCLOPENTAPEPTIDES AND USES THEREOF | ANXA4, CPA4, PTMS | CYP1A2 1504/4885CYP2D6 1488/4885PGR 3660/4885 |
| US-20130129622-A1 | CYCLOPENTAPEPTIDE DERIVATIVES AND USES THEREOF | ANXA4, XPNPEP1, ANXA1 | CYP1A2 2425/4885CYP2D6 1975/4885PGR 2588/4885 |
| US-10919938-B2 | Modified cyclopentapeptides and uses thereof | ANXA4, CPA4, PTMS | CYP1A2 1504/4885CYP2D6 1488/4885PGR 3660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.