⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5923884 | 0.81 | KDM4E (0.33) | — | |
| SCHEMBL28415173 | 0.74 | CA12 (0.33) | — | |
| SCHEMBL11666474 | 0.69 | MEN1 (0.38) | — | |
| SCHEMBL5028270 | 0.69 | — | — | |
| SCHEMBL20156798 | 0.68 | KDM4E (0.40) | — | |
| SCHEMBL23366314 | 0.68 | HPGD (0.39) | — | |
| SCHEMBL4987729 | 0.68 | — | — | |
| SCHEMBL22698156 | 0.68 | — | — | |
| SCHEMBL13787656 | 0.68 | — | — | |
| SCHEMBL1050861 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4405343-A1 | PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2024-07-31 | — | — | EP | disclosed |
| WO-2023046698-A1 | PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-03-30 | — | — | WO | disclosed |
| US-20230015063-A1 | METAL-ASSISTED DELAYED FLUORESCENT EMITTERS CONTAINING TRIDENTATE LIGANDS | UNIV ARIZONA STATE (US) | 2023-01-19 | — | — | US | disclosed |