SCHEMBL2492418

SCHEMBL2492418

CCCC(C)C1CCC2=C(C1)C(=O)c1ccccc1C2=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 7/20 0.34
ALDH1A1 P00352 6/20 0.34
MAPT P10636 6/20 0.34
NPC1 O15118 4/20 0.34
RAB9A P51151 4/20 0.34
LMNA P02545 1/20 0.34
MAPK1 P28482 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
DHODH Q02127 1/20 0.33
AKT1 P31749 3/20 0.33
PKM P14618 3/20 0.33
TP53 P04637 2/20 0.33
MAPK10 P53779 2/20 0.33
IDO1 P14902 1/20 0.33
PTPN1 P18031 2/20 0.32
SLC25A5 P05141 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
MITF O75030 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30397694 1.00 SMN1; SMN2 (0.34) SMN1; SMN2ALDH1A1MAPTNPC1RAB9A
SCHEMBL2490945 0.88 MAPT (0.36) SMN1; SMN2ALDH1A1MAPTNPC1RAB9A
SCHEMBL2491377 0.82 IDO1 (0.37) SMN1; SMN2ALDH1A1MAPTNPC1RAB9A
SCHEMBL7048891 0.79 IDO1 (0.36) SMN1; SMN2ALDH1A1MAPTNPC1RAB9A
SCHEMBL28281311 0.75 AKT1 (0.40) SMN1; SMN2ALDH1A1MAPTNPC1RAB9A
SCHEMBL30393799 0.74 LMNA (0.39) SMN1; SMN2ALDH1A1MAPTNPC1RAB9A
SCHEMBL183347 0.74 LMNA (0.39) SMN1; SMN2ALDH1A1MAPTNPC1RAB9A
Anthraquinone SCHEMBL28278072 0.73 LMNA (0.41) SMN1; SMN2ALDH1A1MAPTNPC1RAB9A
SCHEMBL11878454 0.72 CYP1A2 (0.39) SMN1; SMN2ALDH1A1MAPTNPC1RAB9A
SCHEMBL9004509 0.72 AKT1 (0.34) SMN1; SMN2ALDH1A1MAPTAKT1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8344167-B2 Method for producing propylene oxide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-01-01 US disclosed
EP-2173731-B1 METHOD FOR PRODUCING PROPYLENE OXIDE SUMITOMO CHEMICAL CO (JP) 2011-10-26 EP disclosed
US-20100197946-A1 METHOD FOR PRODUCING PROPYLENE OXIDE SUMITOMO CHEMICAL COMPANY , LIMITED 2010-08-05 US disclosed
EP-2173731-A2 METHOD FOR PRODUCING PROPYLENE OXIDE Sumitomo Chemical Company, Limited (JP) 2010-04-14 EP disclosed
WO-2009008493-A2 METHOD FOR PRODUCING PROPYLENE OXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-15 WO disclosed