⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27634624 | 0.92 | HRH4 (0.34) | — | |
| SCHEMBL28184638 | 0.82 | — | — | |
| SCHEMBL20599409 | 0.80 | — | — | |
| SCHEMBL10641635 | 0.75 | — | — | |
| SCHEMBL29985781 | 0.72 | ALDH1A1 (0.41) | — | |
| SCHEMBL4588217 | 0.71 | — | — | |
| SCHEMBL27459053 | 0.69 | KMT2A (0.41) | — | |
| Hydrochloric Acid SCHEMBL17361360 | 0.69 | — | — | |
| SCHEMBL27944220 | 0.69 | — | — | |
| SCHEMBL14917108 | 0.69 | PARP1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12024510-B2 | Pyrazolopyridine-diamides, their use as insecticide and processes for preparing the same | PI INDUSTRIES LTD. (IN) | 2024-07-02 | — | — | US | disclosed |
| CN-117529315-A | Imidazole-containing ALK2 kinase inhibitors | 生物水晶制药公司 | 2024-02-06 | — | — | CN | disclosed |
| US-20200339578-A1 | PYRAZOLOPYRIDINE-DIAMIDES, THEIR USE AS INSECTICIDE AND PROCESSES FOR PREPARING THE SAME | PI INDUSTRIES LTD. (IN) | 2020-10-29 | — | — | US | disclosed |
| EP-2379545-A1 | 2- (PIPERIDIN-1-YL) -4-AZOLYL-THIAZOLE-5-CARBOXYLIC ACID DERIVATIVES AGAINST BACTERIAL INFECTIONS | AstraZeneca AB (SE) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010067125-A1 | 2- (PIPERIDIN-1-YL) -4-AZOLYL-THIAZOLE-5-CARBOXYLIC ACID DERIVATIVES AGAINST BACTERIAL INFECTIONS | ASTRAZENECA AB (SE) | 2010-06-17 | — | — | WO | disclosed |