Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 7/20 | 0.36 |
| ▸ | CDC25B | P30305 | 7/20 | 0.36 |
| ▸ | CDC25C | P30307 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 7/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24925397 | 0.93 | CDC25A (0.41) | CDC25ACDC25BCDC25CALDH1A1TDP1 | |
| SCHEMBL23338260 | 0.81 | — | — | |
| SCHEMBL24925289 | 0.73 | CDC25A (0.39) | CDC25ACDC25BCDC25CALDH1A1TDP1 | |
| SCHEMBL23581852 | 0.73 | CDC25A (0.56) | CDC25ACDC25BCDC25CALDH1A1TDP1 | |
| SCHEMBL24925115 | 0.72 | — | — | |
| SCHEMBL15268000 | 0.72 | CDC25A (0.40) | CDC25ACDC25BCDC25CALDH1A1TDP1 | |
| SCHEMBL6237311 | 0.72 | CDC25A (0.59) | CDC25ACDC25BCDC25CALDH1A1TDP1 | |
| SCHEMBL7197063 | 0.72 | CDC25A (0.59) | CDC25ACDC25BCDC25CALDH1A1TDP1 | |
| SCHEMBL10908238 | 0.72 | CDC25A (0.59) | CDC25ACDC25BCDC25CALDH1A1TDP1 | |
| SCHEMBL6238660 | 0.72 | CDC25A (0.59) | CDC25ACDC25BCDC25CALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230025922-A1 | USE OF ITACONATE AND ITS DERIVATIVES/ANALOGUES TO INDUCE HAIR GROWTH | THE JOHNS HOPKINS UNIVERSTY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025922-A1 | USE OF ITACONATE AND ITS DERIVATIVES/ANALOGUES TO INDUCE HAIR GROWTH | LRBA, HADHA, IMPDH1 | CDC25A 277/4885CDC25B 458/4885CDC25C 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.