SCHEMBL24925307

SCHEMBL24925307

Cc1ccc(F)cc1OC1CCCC1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EIF4E P06730 1/20 0.43
MKNK1 Q9BUB5 1/20 0.43
MKNK2 Q9HBH9 1/20 0.43
SCD O00767 4/20 0.42
OXTR P30559 2/20 0.40
AVPR1A P37288 2/20 0.40
AVPR2 P30518 1/20 0.40
SLC6A2 P23975 2/20 0.40
SLC6A4 P31645 2/20 0.40
CYP2D6 P10635 1/20 0.40
PDE4A P27815 3/20 0.39
ABL1 P00519 1/20 0.38
KCNH2 Q12809 1/20 0.37
CSNK2A1 P68400 1/20 0.37
OPRL1 P41146 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24925309 0.93 SCD (0.44) EIF4EMKNK1MKNK2SCDOXTR
SCHEMBL15696522 0.86 OXTR (0.41) SCDOXTRAVPR1AAVPR2SLC6A2
SCHEMBL14409244 0.86 OXTR (0.44) EIF4EMKNK1MKNK2OXTRAVPR1A
SCHEMBL15800229 0.85 SLC6A2 (0.40) MKNK1MKNK2SCDOXTRAVPR1A
SCHEMBL24780615 0.85 SYK (0.51) MKNK1MKNK2SCDOXTRAVPR1A
SCHEMBL15696489 0.85 SLC6A2 (0.40) MKNK1MKNK2SCDOXTRAVPR1A
SCHEMBL15800215 0.85 SLC6A2 (0.40) MKNK1MKNK2SCDOXTRAVPR1A
SCHEMBL1231616 0.85 SLC6A2 (0.51) SLC6A2SLC6A4
SCHEMBL15800216 0.84 OXTR (0.39) EIF4EMKNK1MKNK2SCDOXTR
SCHEMBL15800244 0.84 OXTR (0.39) EIF4EMKNK1MKNK2SCDOXTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230303495-A9 PYRIDINE OXYNITRIDE, PREPARATION METHOD THEREFOR AND USE THEREOF SHANGHAI JEYOU PHARMACEUTICAL CO., LTD. (CN) 2023-09-28 US disclosed
US-20230303495-A9 PYRIDINE OXYNITRIDE, PREPARATION METHOD THEREFOR AND USE THEREOF SHANGHAI JEYOU PHARMACEUTICAL CO., LTD. (CN) 2023-09-28 US disclosed
US-20230026907-A1 PYRIDINE OXYNITRIDE, PREPARATION METHOD THEREFOR AND USE THEREOF ORION CORP (FI) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230026907-A1 PYRIDINE OXYNITRIDE, PREPARATION METHOD THEREFOR AND USE THEREOF SCN11A, HCN4, CACNA1F EIF4E 4747/4885MKNK1 4232/4885MKNK2 4293/4885
US-20230303495-A9 PYRIDINE OXYNITRIDE, PREPARATION METHOD THEREFOR AND USE THEREOF SCN11A, HCN4, CACNA1F EIF4E 4747/4885MKNK1 4232/4885MKNK2 4293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.