SCHEMBL24925405

SCHEMBL24925405

CC1(C)Cn2cncc2C1=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.33
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1180242 0.81 CYP1A2 (0.38) IDO1
SCHEMBL24925406 0.79 TSHR (0.31) IDO1
SCHEMBL14249405 0.67 RAB9A (0.35) RAB9ASMN1; SMN2
SCHEMBL18338406 0.65 SMN1; SMN2 (0.34) RAB9ASMN1; SMN2
SCHEMBL24730818 0.62 MAPKAPK2 (0.34) IDO1
SCHEMBL24730822 0.62 MAPKAPK2 (0.34) IDO1
SCHEMBL1180985 0.59 IDO1 (0.32) IDO1
SCHEMBL25082072 0.59
SCHEMBL1737418 0.59 IDO1 (0.34) IDO1SMN1; SMN2
SCHEMBL18338385 0.56 CYP1A2 (0.44) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230014226-A1 NEW COMPOUNDS AND METHODS BENEVOLENTAI BIO LIMITED (GB) 2023-01-19 US disclosed
CN-114340734-A Novel compounds and methods 博善人工智能生物科技有限公司 2022-04-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230014226-A1 NEW COMPOUNDS AND METHODS ABL2, ABL1, ALK IDO1 2511/4885RAB9A 1661/4885SMN1; SMN2 2246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.