Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21106247 | 0.87 | KDM4E (0.36) | TSHRKDM4ERECQL | |
| SCHEMBL26018451 | 0.83 | HTT (0.41) | TSHR | |
| SCHEMBL25725953 | 0.83 | HRH3 (0.31) | — | |
| SCHEMBL21933642 | 0.83 | — | — | |
| SCHEMBL5932102 | 0.81 | TSHR (0.43) | TSHRKDM4ERECQLLMNA | |
| SCHEMBL10959162 | 0.81 | TSHR (0.43) | TSHRKDM4ERECQLLMNA | |
| SCHEMBL25826994 | 0.81 | CYP2C19 (0.37) | TSHRKDM4ERECQL | |
| SCHEMBL26457722 | 0.81 | — | — | |
| SCHEMBL23341229 | 0.80 | HRH3 (0.32) | — | |
| SCHEMBL24763974 | 0.79 | HRH3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004163-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK WITH ENHANCED IMID ACTIVITY | NURIX THERAPEUTICS, INC. (US) | 2023-01-26 | — | — | WO | disclosed |