Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891066 | 0.91 | GAA (0.38) | GAAALOX15TSHRHSD17B10ALDH1A1 | |
| SCHEMBL23594595 | 0.86 | GAA (0.36) | GAAALOX15TSHRHSD17B10ALDH1A1 | |
| SCHEMBL24891049 | 0.86 | GAA (0.36) | GAAALOX15TSHRHSD17B10ALDH1A1 | |
| SCHEMBL24926276 | 0.78 | GAA (0.34) | GAAALOX15TSHRHSD17B10ALDH1A1 | |
| SCHEMBL24220815 | 0.74 | GAA (0.44) | GAAALOX15TSHRHSD17B10ALDH1A1 | |
| SCHEMBL24357171 | 0.74 | POLB (0.54) | GAAALOX15TSHRHSD17B10ALDH1A1 | |
| SCHEMBL15496587 | 0.73 | HSD17B10 (0.44) | HSD17B10ALDH1A1SMN1; SMN2TACR1KDM4E | |
| SCHEMBL13519659 | 0.72 | SIGMAR1 (0.48) | ALDH1A1SMN1; SMN2MAPTTACR1KDM4E | |
| SCHEMBL23509410 | 0.72 | TP53 (0.39) | ALDH1A1SMN1; SMN2TACR1KDM4EPIK3CD | |
| SCHEMBL23842296 | 0.71 | TACR1 (0.46) | HSD17B10ALDH1A1MAPTTACR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004163-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK WITH ENHANCED IMID ACTIVITY | NURIX THERAPEUTICS, INC. (US) | 2023-01-26 | — | — | WO | disclosed |