Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249257 | 1.00 | SCN5A (0.47) | SCN5ASCN9ASCN10ATSHR | |
| SCHEMBL561223 | 0.95 | TSHR (0.47) | SCN5ASCN9ASCN10ATSHR | |
| SCHEMBL2016482 | 0.88 | SCN5A (0.48) | SCN5ASCN9ASCN10A | |
| SCHEMBL27799993 | 0.81 | — | — | |
| SCHEMBL28748508 | 0.79 | SCN5A (0.40) | SCN5ASCN9ASCN10A | |
| SCHEMBL6838437 | 0.78 | TSHR (0.50) | TSHR | |
| SCHEMBL19236578 | 0.76 | TSHR (0.47) | SCN5ASCN9ASCN10ATSHR | |
| SCHEMBL6023367 | 0.76 | TSHR (0.44) | TSHR | |
| SCHEMBL17533289 | 0.76 | SCN5A (0.39) | SCN5ASCN9ASCN10A | |
| SCHEMBL17533287 | 0.76 | SCN5A (0.39) | SCN5ASCN9ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152651-B1 | THERAPEUTIC COMPOUNDS | PHARMACOFORE INC (US) | 2012-01-04 | — | — | EP | claimed |
| EP-2152651-B1 | THERAPEUTIC COMPOUNDS | PHARMACOFORE INC (US) | 2012-01-04 | — | — | EP | disclosed |