SCHEMBL6023367

SCHEMBL6023367

CCC(C)c1cccc(C(C)CC)c1OC(=O)NC

nearest known ligand 0.70

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
ALDH1A1 P00352 1/20 0.44
ACHE P22303 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5567711 0.83
Fenobucarb SCHEMBL6740176 0.83 ALDH1A1 (0.58) TSHRALDH1A1ACHE
Fenobucarb SCHEMBL29368514 0.83 ALDH1A1 (0.58) TSHRALDH1A1ACHE
Fenobucarb SCHEMBL73674 0.83 ALDH1A1 (0.58) TSHRALDH1A1ACHE
SCHEMBL27799993 0.82
SCHEMBL561223 0.80 TSHR (0.47) TSHR
SCHEMBL10033208 0.80 MEN1 (0.51) ALDH1A1
SCHEMBL560467 0.80 MEN1 (0.51) ALDH1A1
SCHEMBL3635759 0.78 NPC1 (0.53) TSHR
SCHEMBL3435870 0.77 MEN1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1651034-A2 ORGANIC COMPOUNDS Novartis AG (CH) 2006-05-03 EP claimed
WO-2005013687-A2 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2005-02-17 WO claimed
EP-1504664-A1 Organic compounds Novartis AG (CH) 2005-02-09 EP claimed
EP-1651034-A2 ORGANIC COMPOUNDS Novartis AG (CH) 2006-05-03 EP disclosed
WO-2005013687-A2 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2005-02-17 WO disclosed
EP-1504664-A1 Organic compounds Novartis AG (CH) 2005-02-09 EP disclosed
US-4205066-A Bait compositions for anthropophilic flies AIRWICK INDUSTRIES, INC. (US) 1980-05-27 US disclosed