Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 17/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20098266 | 0.83 | TSHR (0.31) | — | |
| SCHEMBL18948528 | 0.80 | — | — | |
| SCHEMBL20738601 | 0.80 | TRPV3 (0.33) | TRPV3 | |
| SCHEMBL1438816 | 0.80 | TRPV3 (0.33) | TRPV3 | |
| SCHEMBL1438814 | 0.80 | TRPV3 (0.33) | TRPV3 | |
| SCHEMBL588457 | 0.79 | PDE2A (0.33) | TRPV3PDE2APDE10A | |
| SCHEMBL30374033 | 0.79 | PDE2A (0.33) | TRPV3PDE2APDE10A | |
| SCHEMBL12190549 | 0.78 | PDE2A (0.40) | PDE2APDE10A | |
| SCHEMBL589064 | 0.75 | IRAK4 (0.35) | PDE2APDE10A | |
| SCHEMBL19003646 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230019032-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230019032-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | MAPK1, ALK, MAP3K1 | TRPV3 3835/4885ABCB11 2337/4885PDE2A 4453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.