Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | QDPR | P09417 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | HCK | P08631 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 5/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25302525 | 0.84 | PDE4A (0.34) | SLC6A4QDPRPDE4APDE4BPDE4C | |
| SCHEMBL30181349 | 0.81 | QDPR (0.49) | QDPRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16784800 | 0.81 | QDPR (0.49) | QDPRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29276019 | 0.81 | PTGDR (0.39) | SLC6A4QDPRALDH1A1PDE4APDE4B | |
| SCHEMBL31309037 | 0.78 | QDPR (0.41) | QDPREGFRPDE4APDE4BPDE4C | |
| SCHEMBL24313719 | 0.77 | PDE4A (0.35) | SLC6A4QDPRKDM4EALDH1A1PDE4A | |
| SCHEMBL2129892 | 0.77 | PDE4A (0.35) | QDPRKDM4EALDH1A1PDE4APDE4B | |
| SCHEMBL5883269 | 0.76 | CYP19A1 (0.38) | PDE4APDE4BPDE4CPDE4DROR1 | |
| SCHEMBL31019754 | 0.75 | PDE4A (0.47) | QDPRALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL23288648 | 0.75 | QDPR (0.46) | QDPRPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023003002-A1 | ANNULATED PYRIDAZINE COMPOUND | アステラス製薬株式会社 | 2023-01-26 | — | — | WO | disclosed |