Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24926579 | 0.82 | PIK3CD (0.32) | PIK3CDMLYCDMAPTPOLB | |
| SCHEMBL23368125 | 0.80 | — | — | |
| SCHEMBL3216320 | 0.79 | KMT2A (0.35) | PIK3CDMLYCDMAPTPOLB | |
| SCHEMBL1233264 | 0.73 | POLB (0.33) | PIK3CDPOLB | |
| SCHEMBL10663361 | 0.73 | NAALAD2 (0.31) | — | |
| SCHEMBL154812 | 0.72 | POLB (0.46) | PIK3CDMLYCDMAPTPOLB | |
| SCHEMBL27264586 | 0.71 | PIK3CD (0.34) | PIK3CDPOLB | |
| SCHEMBL27252869 | 0.71 | — | — | |
| SCHEMBL22304297 | 0.70 | PIK3CD (0.37) | PIK3CDMLYCDMAPTPOLB | |
| SCHEMBL10175141 | 0.70 | MLYCD (0.38) | MLYCDMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230025510-A1 | BIARYL ETHER-TYPE QUINAZOLINE DERIVATIVES | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025510-A1 | BIARYL ETHER-TYPE QUINAZOLINE DERIVATIVES | ERBB2, EGFR, ERBB3 | PIK3CD 187/4885MLYCD 4198/4885MAPT 4074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.