Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.41 |
| ▸ | PPARD | Q03181 | 9/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CTSA | P10619 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464909 | 0.91 | PPARA (0.50) | PPARAPPARDPPARGHTT | |
| SCHEMBL2492775 | 0.87 | PPARA (0.55) | PPARAPPARDPPARG | |
| SCHEMBL2464883 | 0.85 | PPARD (0.41) | PPARAPPARDPPARGHTTNR1H4 | |
| SCHEMBL2462553 | 0.84 | PPARD (0.39) | PPARAPPARDPPARGNR1H4THRA | |
| SCHEMBL2467702 | 0.83 | ABCB1 (0.38) | PPARAPPARDPPARGNR1H4 | |
| SCHEMBL376651 | 0.81 | PPARA (0.55) | PPARAPPARDPPARG | |
| SCHEMBL2464201 | 0.78 | PPARD (0.49) | PPARAPPARDPPARGCTSA | |
| SCHEMBL1765850 | 0.78 | PPARD (0.49) | PPARAPPARDPPARGCTSA | |
| SCHEMBL2464908 | 0.77 | PPARA (0.65) | PPARAPPARDPPARG | |
| SCHEMBL2466327 | 0.75 | PPARA (0.45) | PPARAPPARDPPARGCTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1424330-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA | NIPPON CHEMIPHAR CO (JP) | 2011-09-28 | — | — | EP | disclosed |