Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 6/20 | 0.35 |
| ▸ | PPARA | Q07869 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464883 | 0.91 | PPARD (0.41) | PPARDPPARAPPARGNR1H4 | |
| SCHEMBL2464909 | 0.84 | PPARA (0.50) | PPARDPPARAPPARG | |
| SCHEMBL2492777 | 0.83 | PPARA (0.41) | PPARDPPARAPPARGNR1H4 | |
| SCHEMBL1765914 | 0.78 | PPARD (0.57) | PPARDPPARAPPARG | |
| SCHEMBL12732403 | 0.78 | PPARD (0.50) | PPARDPPARAPPARG | |
| SCHEMBL2467481 | 0.77 | PPARD (0.38) | PPARDPPARAPPARG | |
| SCHEMBL2466122 | 0.77 | PPARD (0.45) | HPGDHSD17B10PPARDPPARAMAPT | |
| SCHEMBL2462566 | 0.77 | PPARD (0.40) | HPGDHSD17B10PPARDPPARAMAPT | |
| SCHEMBL4752337 | 0.77 | PPARG (0.34) | KDM4EPPARDPPARAMAPTPPARG | |
| SCHEMBL2463130 | 0.77 | WNT3A (0.36) | HSD17B10PPARDPPARAPPARGNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1424330-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA | NIPPON CHEMIPHAR CO (JP) | 2011-09-28 | — | — | EP | disclosed |