SCHEMBL24928178

SCHEMBL24928178

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc4c3sc3c(-c5ccc(-c6ccc7c(c6)oc6ccccc67)c6sc7ccccc7c56)cccc34)n2)cc1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 7/20 0.42
ALOX5 P09917 2/20 0.40
PIK3CD O00329 2/20 0.32
PIK3CB P42338 2/20 0.32
BRD4 O60885 1/20 0.31
PIK3CA P42336 1/20 0.31
MTOR P42345 1/20 0.31
PIK3CG P48736 1/20 0.31
KCNH2 Q12809 1/20 0.31
BRDT Q58F21 1/20 0.31
LIMK1 P53667 1/20 0.30
TERT O14746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24929456 0.92 PRKDC (0.44) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL24929689 0.92 PRKDC (0.40) PRKDCALOX5LIMK1
SCHEMBL24928181 0.91 ALOX5 (0.38) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL24929427 0.91 PRKDC (0.38) PRKDCALOX5LIMK1
SCHEMBL22135492 0.91 PRKDC (0.44) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL23349796 0.91 PRKDC (0.40) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL24928185 0.90 ALOX5 (0.42) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL24929930 0.89 PRKDC (0.42) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL24929615 0.89 ALOX5 (0.41) PRKDCALOX5PIK3CDPIK3CBLIMK1
SCHEMBL24216006 0.89 PRKDC (0.43) PRKDCALOX5PIK3CDPIK3CBBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023008795-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2023-02-02 WO disclosed