Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.60 |
| ▸ | ALB | P02768 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | FASN | P49327 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24928294 | 0.90 | TTR (0.55) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL24928450 | 0.90 | TTR (0.55) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL24928570 | 0.90 | RAB9A (0.60) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL24928446 | 0.88 | TTR (0.63) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL24928296 | 0.87 | TTR (0.62) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL24928568 | 0.86 | RAB9A (0.68) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL24928298 | 0.85 | TTR (0.65) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL24163196 | 0.85 | TTR (0.67) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL24928503 | 0.84 | TTR (0.66) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL24928289 | 0.83 | TTR (0.62) | TTRALBMAOACNR1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009585-A2 | TRANSTHYRETIN STABILIZING COMPOUNDS | PROTEGO BIOPHARMA, INC. (US) | 2023-02-02 | — | — | WO | disclosed |