Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 6/20 | 0.58 |
| ▸ | FABP3 | P05413 | 2/20 | 0.58 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2946584 | 0.84 | FABP4 (0.62) | FABP4FABP3FABP5ALDH1A1ENPP3 | |
| SCHEMBL14949312 | 0.82 | FABP4 (0.60) | FABP4FABP3FABP5ALDH1A1ENPP3 | |
| SCHEMBL17131628 | 0.81 | FABP4 (0.58) | FABP4FABP3FABP5ALDH1A1ENPP3 | |
| SCHEMBL8172825 | 0.81 | FABP4 (0.58) | FABP4FABP3FABP5ALDH1A1ENPP3 | |
| SCHEMBL7807949 | 0.81 | FABP4 (0.58) | FABP4FABP3FABP5ALDH1A1ENPP3 | |
| SCHEMBL11887242 | 0.78 | FABP4 (0.55) | FABP4FABP3FABP5ALDH1A1ENPP3 | |
| SCHEMBL11888501 | 0.78 | FABP4 (0.55) | FABP4FABP3FABP5ALDH1A1ENPP3 | |
| SCHEMBL19222219 | 0.78 | FABP4 (0.50) | FABP4FABP3FABP5ALDH1A1ENPP3 | |
| SCHEMBL8989764 | 0.77 | FABP4 (0.69) | FABP4FABP3FABP5ALDH1A1ENPP3 | |
| SCHEMBL28317081 | 0.77 | FABP4 (0.53) | FABP4FABP3FABP5ALDH1A1ENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230029385-A1 | 2-METHYL-AZA-QUINAZOLINES | BAYER AG (DE) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230029385-A1 | 2-METHYL-AZA-QUINAZOLINES | AZI2, DNMT1, TPMT | FABP4 4780/4885FABP3 4835/4885FABP5 4249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.