Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385029 | 1.00 | KCNH2 (0.44) | KCNH2CTSCCYP2C19SMN1; SMN2AGTR2 | |
| SCHEMBL6238616 | 1.00 | KCNH2 (0.44) | KCNH2CTSCCYP2C19SMN1; SMN2AGTR2 | |
| SCHEMBL16920345 | 0.88 | CTSC (0.44) | CTSCAGTR2EPHX2CTSLCTSB | |
| SCHEMBL1006306 | 0.88 | CTSC (0.44) | CTSCAGTR2EPHX2CTSLCTSB | |
| SCHEMBL1768681 | 0.88 | CTSC (0.44) | CTSCAGTR2EPHX2CTSLCTSB | |
| SCHEMBL6374726 | 0.88 | CTSC (0.44) | CTSCAGTR2EPHX2CTSLCTSB | |
| SCHEMBL5802417 | 0.88 | CTSC (0.44) | CTSCAGTR2EPHX2CTSLCTSB | |
| SCHEMBL1006317 | 0.88 | CTSC (0.44) | CTSCAGTR2EPHX2CTSLCTSB | |
| SCHEMBL1006316 | 0.88 | CTSC (0.44) | CTSCAGTR2EPHX2CTSLCTSB | |
| SCHEMBL30439054 | 0.87 | KCNH2 (0.49) | KCNH2CYP2C19SMN1; SMN2AGTR2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009585-A2 | TRANSTHYRETIN STABILIZING COMPOUNDS | PROTEGO BIOPHARMA, INC. (US) | 2023-02-02 | — | — | WO | disclosed |