SCHEMBL1006306

SCHEMBL1006306

O=C(O)[C@@H]1C[C@@H](OCc2ccccc2)CN1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CTSC P53634 1/20 0.44
GRIK1 P39086 3/20 0.43
AGTR2 P50052 2/20 0.43
GRIA2 P42262 1/20 0.43
ALDH1A1 P00352 2/20 0.41
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
CTSK P43235 1/20 0.41
EPHX2 P34913 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16920345 1.00 CTSC (0.44) CTSCGRIK1AGTR2GRIA2ALDH1A1
SCHEMBL1768681 1.00 CTSC (0.44) CTSCGRIK1AGTR2GRIA2ALDH1A1
SCHEMBL1006317 1.00 CTSC (0.44) CTSCGRIK1AGTR2GRIA2ALDH1A1
SCHEMBL6374726 1.00 CTSC (0.44) CTSCGRIK1AGTR2GRIA2ALDH1A1
SCHEMBL5802417 1.00 CTSC (0.44) CTSCGRIK1AGTR2GRIA2ALDH1A1
SCHEMBL1006316 1.00 CTSC (0.44) CTSCGRIK1AGTR2GRIA2ALDH1A1
Hydrochloric Acid SCHEMBL7449326 0.98 GRIK1 (0.45) CTSCGRIK1AGTR2GRIA2CTSL
Hydrochloric Acid SCHEMBL5862746 0.98 GRIK1 (0.45) CTSCGRIK1AGTR2GRIA2CTSL
Hydrochloric Acid SCHEMBL5862743 0.98 GRIK1 (0.45) CTSCGRIK1AGTR2GRIA2CTSL
SCHEMBL8881468 0.93 CTSC (0.40) CTSCGRIK1AGTR2GRIA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250171495-A1 MUTLI-TARGETED SERINE PROTEASE INHIBITORS FOR TREATMENT OF CANCER AND VIRAL INFECTION WASHINGTON UNIVERSITY 2025-05-29 US claimed
EP-4448547-A1 APELINERGIC MACROCYCLES AND USES THEREOF Socpra Sciences Santé Et Humaines S.E.C. (CA) 2024-10-23 EP claimed
US-20240343761-A1 APELINERGIC MACROCYCLES AND USES THEREOF SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2024-10-17 US claimed
US-12077611-B2 Cyclic peptides multimers targeting α4β7 integrin ZEALAND PHARMA A/S (DK) 2024-09-03 US claimed
US-20230406884-A1 CYCLIC PEPTIDES MULTIMERS TARGETING ALPHA-4-BETA-7 INTEGRIN ZEALAND PHARMA A/S (DK) 2023-12-21 US claimed
WO-2023108291-A9 APELINERGIC MACROCYCLES AND USES THEREOF SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2023-09-28 WO claimed
US-11713338-B2 Cyclic peptides multimers targeting α-4-β-7 integrin ZEALAND PHARMA A/S (DK) 2023-08-01 US claimed
WO-2023108291-A1 APELINERGIC MACROCYCLES AND USES THEREOF SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2023-06-22 WO claimed
EP-4100040-A1 DIAMINE-LINKED RECEPTOR-SPECIFIC CYCLIC PEPTIDES Palatin Technologies, Inc. (US) 2022-12-14 EP claimed
EP-4100042-A1 REVERSE AMIDE-LINKED MELANOCORTIN RECEPTOR-SPECIFIC CYCLIC PEPTIDES Palatin Technologies, Inc. (US) 2022-12-14 EP claimed
US-20220363719-A1 Reverse Amide-Linked Melanocortin Receptor-Specific Cyclic Peptides PALATIN TECHNOLOGIES, INC. (US) 2022-11-17 US claimed
WO-2026105061-A1 ANTIBODY-DRUG CONJUGATES THAT BIND CDCP1 AND USES THEREOF PHEON THERAPEUTICS LTD (GB) 2026-05-21 WO disclosed
US-20260125418-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT OWLSTONE MED LTD (GB) 2026-05-07 US disclosed
WO-2026090584-A2 METHODS OF TREATING PERIPHERAL NERVOUS SYSTEM MYELINATION CONDITIONS Artery Therapeutics, Inc. (US) 2026-04-30 WO disclosed
EP-4731270-A1 COMBINATION THERAPY WITH PEPTIDE RECEPTOR RADIONUCLIDE AND DNA REPAIR INHIBITOR The Regents of The University of California (US) 2026-04-29 EP disclosed
US-20030055094-A1 Bicyclic modulators of androgen receptor function BRISTOL-MYERS SQUIBB COMPANY 2003-03-20 US disclosed
CN-1353701-A Peptidyl heterocyclic ketones useful as tryptase inhibitors ORTHO MCNEIL PHARM INC (US) 2002-06-12 CN disclosed
US-6143715-A FOR TREATING AND PREVENTION OF HEPATITIS C VIURS INFECTIONS BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 2000-11-07 US disclosed
WO-1995033763-A1 NOVEL ELASTASE INHIBITORS HOECHST MARION ROUSSEL, INC. (US) 1995-12-14 WO disclosed
US-4316906-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1982-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171495-A1 MUTLI-TARGETED SERINE PROTEASE INHIBITORS FOR TREATMENT OF CANCER AND VIRAL INFECTION TMPRSS2, PRSS1, PRSS2 CTSC 93/4885GRIK1 3611/4885AGTR2 1026/4885
US-20220363719-A1 Reverse Amide-Linked Melanocortin Receptor-Specific Cyclic Peptides MC1R, NPY1R, MC3R CTSC 1594/4885GRIK1 1049/4885AGTR2 358/4885
US-20260125418-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT BRCA1, L3MBTL1, LMNA CTSC 2040/4885GRIK1 4414/4885AGTR2 4162/4885
US-20240343761-A1 APELINERGIC MACROCYCLES AND USES THEREOF APLNR, AP3D1, AP3B1 CTSC 261/4885GRIK1 746/4885AGTR2 7/4885
US-12077611-B2 Cyclic peptides multimers targeting α4β7 integrin ITGB7, ITGB4, ITGA4 CTSC 1717/4885GRIK1 2361/4885AGTR2 2113/4885
US-20030055094-A1 Bicyclic modulators of androgen receptor function AR, NR5A1, ESRRA CTSC 1726/4885GRIK1 1345/4885AGTR2 245/4885
US-20230406884-A1 CYCLIC PEPTIDES MULTIMERS TARGETING ALPHA-4-BETA-7 INTEGRIN ITGB7, ITGB4, ITGA4 CTSC 1174/4885GRIK1 2309/4885AGTR2 1642/4885
US-11713338-B2 Cyclic peptides multimers targeting α-4-β-7 integrin ITGB7, ITGB4, ITGA4 CTSC 1198/4885GRIK1 2404/4885AGTR2 1632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.