Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 10/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31198454 | 1.00 | ACLY (0.37) | ACLYPTK2BSMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL24928715 | 0.98 | ACLY (0.37) | ACLYPTK2BSMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL30153301 | 0.98 | ACLY (0.37) | ACLYPTK2BSMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL30153205 | 0.91 | ACLY (0.35) | ACLYPTK2BSMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL24928721 | 0.91 | ACLY (0.35) | ACLYPTK2BSMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL24928646 | 0.90 | ACLY (0.45) | ACLYPTK2BSMN1; SMN2TDP1FABP4 | |
| SCHEMBL31198407 | 0.90 | ACLY (0.45) | ACLYPTK2BSMN1; SMN2TDP1FABP4 | |
| SCHEMBL24928649 | 0.86 | ACLY (0.41) | ACLYTDP1FABP4PDE4APDE4B | |
| SCHEMBL30153363 | 0.86 | ACLY (0.41) | ACLYTDP1FABP4PDE4APDE4B | |
| SCHEMBL30153331 | 0.84 | ACLY (0.38) | ACLYSMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007188-A1 | PHENYL-SULFAMOYL-BENZOIC ACID DERIVATIVES AS ERAP1- MODULATORS | Grey Wolf Therapeutics Limited (GB) | 2023-02-02 | — | — | WO | disclosed |