SCHEMBL2492866

SCHEMBL2492866

c1ccc(-c2cccc3c2O3)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.45
ALDH1A1 P00352 4/20 0.41
HSD17B10 Q99714 2/20 0.41
MAPK1 P28482 2/20 0.41
HPGD P15428 1/20 0.41
BCL2L1 Q07817 1/20 0.41
CYP2A6 P11509 1/20 0.41
NTSR1 P30989 1/20 0.39
GPR55 Q9Y2T6 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
ADRA2A P08913 2/20 0.39
ADRA2B P18089 2/20 0.39
ADRA2C P18825 2/20 0.39
CHRNB4 P30926 2/20 0.38
CHRNA3 P32297 2/20 0.38
BACE1 P56817 1/20 0.37
DPP4 P27487 1/20 0.37
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29680062 1.00 AHR (0.45) AHRALDH1A1HSD17B10MAPK1HPGD
SCHEMBL9041365 0.86 HDAC4 (0.38) ATMADRA2AADRA2BADRA2CHNF4A
SCHEMBL18967548 0.85 MAPK1 (0.44) AHRALDH1A1HSD17B10MAPK1HPGD
SCHEMBL17362259 0.83 NTSR1 (0.43) AHRALDH1A1HSD17B10MAPK1HPGD
SCHEMBL17482453 0.82 AHR (0.36) AHRALDH1A1HSD17B10MAPK1HPGD
SCHEMBL16787207 0.82 AHR (0.41) AHRALDH1A1MAPK1NTSR1GPR55
SCHEMBL30493572 0.82 AHR (0.48) AHRMAPK1KDM4EATM
SCHEMBL16787185 0.81 AHR (0.40) AHRALDH1A1MAPK1NTSR1GPR55
SCHEMBL28772315 0.81 BACE1 (0.37) AHRALDH1A1HSD17B10MAPK1HPGD
SCHEMBL17485065 0.80 MAPK1 (0.48) AHRALDH1A1HSD17B10MAPK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1164715-C Macromolecular reaction process of preparing side-chain liquid crystal polyimide film 四川大学 2004-09-01 CN claimed
CN-1375537-A Macromolecular reaction process of preparing side-chain liquid crystal polyimide film UNIV SICHUAN (CN) 2002-10-23 CN claimed
CN-112458001-B Bacterial strain capable of degrading polycyclic aromatic hydrocarbon and application thereof 上海交通大学 2022-09-27 CN disclosed
US-11384195-B2 Difunctional biphenyl compounds, preparation, and uses ARIANEGROUP SAS (FR) 2022-07-12 US disclosed
CN-112458001-A Bacterial strain capable of degrading polycyclic aromatic hydrocarbon and application thereof 上海交通大学 2021-03-09 CN disclosed
CN-108219381-A Poly (arylene ether) resin combination 罗门哈斯电子材料有限责任公司 2018-06-29 CN disclosed
JP-2011213996-A EPOXY ACRYLATE, ACRYLIC COMPOSITION, CURED PRODUCT, AND METHOD FOR MANUFACTURING THE SAME NIPPON STEEL CHEM CO LTD 2011-10-27 JP disclosed
EP-1947725-B1 Polymer electrolyte composition and fuel cell SUMITOMO CHEMICAL CO (JP) 2011-10-19 EP disclosed
EP-1947725-A2 Polymer electrolyte composition and fuel cell Sumitomo Chemical Company, Limited (JP) 2008-07-23 EP disclosed
EP-1289041-B1 Polymer electrolyte composition and fuel cell SUMITOMO CHEMICAL CO (JP) 2008-03-12 EP disclosed
US-20060257706-A1 POLYMER ELECTROLYTE COMPOSITION AND FUEL CELL HIDAKA YASUAKI 2006-11-16 US disclosed
CN-1179444-A Epoxy resin composition and semiconductor device encapsulated therewith MITSUBISHI ELECTRIC CORP (JP) 1998-04-22 CN disclosed
CN-1138602-A Semiconductor encapsulating epoxy resin compositions and semiconductor devices encapsulated therewith SHINETSU CHEMICAL CO (JP) 1996-12-25 CN disclosed
US-5380460-A Ferroelectric liquid crystal compounds containing chiral haloalkoxy tail units and compositions containing them DISPLAYTECH, INC. (US) 1995-01-10 US disclosed
WO-1993006192-A1 FERROELECTRIC LIQUID CRYSTAL COMPOUNDS CONTAINING CHIRAL HALOALKOXY TAIL UNITS AND COMPOSITIONS CONTAINING THEM DISPLAYTECH, INCORPORATED (US) 1993-04-01 WO disclosed
US-5138010-A Fast switching polysiloxane ferroelectric liquid crystals UNIVERSITY OF COLORADO FOUNDATION, INC. (US) 1992-08-11 US disclosed
US-5051506-A Compounds for electrooptical displays DISPLAYTECH, INC. (US) 1991-09-24 US disclosed
US-5009999-A Aerobic process using Pseudomonas GENERAL ELECTRIC COMPANY (US) 1991-04-23 US disclosed
US-4843009-A POLLUTION CONTROL OF WATER AND SOIL GENERAL ELECTRIC COMPANY (US) 1989-06-27 US disclosed
US-4104073-A MIXTURE OF SEMI-SOLID OR LIQUID ORGANIC MATERIAL, A NITROGEN-CONTA2NING PHOSPHATE, AND A LUBRICATING GREASE DAINICHI-NIPPON CABLES, LTD. (JP) 1978-08-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11384195-B2 Difunctional biphenyl compounds, preparation, and uses ALK, ALKBH3, AHR AHR 3/4885ALDH1A1 24/4885HSD17B10 1017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.