SCHEMBL24928820

SCHEMBL24928820

CCCCC(CC)CNC(=O)OC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.53
CYP3A4 P08684 3/20 0.53
ALDH1A1 P00352 3/20 0.53
HRH4 Q9H3N8 1/20 0.49
HRH3 Q9Y5N1 1/20 0.49
HTT P42858 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
GLA P06280 1/20 0.49
EPHX1 P07099 1/20 0.48
CA2 P00918 3/20 0.47
CA1 P00915 1/20 0.47
TDP1 Q9NUW8 2/20 0.46
ATM Q13315 1/20 0.46
LMNA P02545 2/20 0.46
POLB P06746 1/20 0.46
MAPK1 P28482 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MMP9 P14780 1/20 0.43
MMP8 P22894 1/20 0.43
MMP14 P50281 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL844954 0.86 HRH4 (0.53) TSHRCYP3A4ALDH1A1HRH4HRH3
SCHEMBL13105120 0.84 EPHX1 (0.43) TSHRHRH4HRH3HTTL3MBTL1
SCHEMBL24719297 0.84 HRH4 (0.49) TSHRCYP3A4ALDH1A1HRH4HRH3
Ammonia Solution, Strong SCHEMBL9998720 0.83 TSHR (0.57) TSHRCYP3A4ALDH1A1HRH4HRH3
SCHEMBL28598856 0.83 TSHR (0.57) TSHRCYP3A4ALDH1A1HRH4HRH3
SCHEMBL10581948 0.83 TSHR (0.47) TSHRCYP3A4ALDH1A1HRH4HRH3
SCHEMBL13045906 0.83 CTSK (0.48) TSHRCYP3A4ALDH1A1HRH4HRH3
SCHEMBL23878446 0.83 TSHR (0.57) TSHRCYP3A4ALDH1A1HRH4HRH3
SCHEMBL3966075 0.82 TSHR (0.59) TSHRCYP3A4ALDH1A1HRH4HRH3
SCHEMBL16312309 0.82 TSHR (0.59) TSHRCYP3A4ALDH1A1HRH4HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023008572-A1 ONIUM SALT, BLOCKING AGENT DISSOCIATION CATALYST FOR BLOCKED ISOCYANATE, BLOCKED ISOCYANTE COMPOSITION INCLUDING BLOCKING AGENT DISSOCIATION CATALYST, THERMOSETTING RESIN COMPOSITION, AND CURED PRODUCT AND MANUFACTURING METHOD THEREFOR 広栄化学株式会社 2023-02-02 WO disclosed