Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5948737 | 0.92 | PLA2G1B (0.30) | — | |
| SCHEMBL5948506 | 0.86 | PLA2G1B (0.34) | — | |
| SCHEMBL35704 | 0.86 | CYP1A2 (0.46) | CYP1A2MAPK1CA12CA1CA2 | |
| SCHEMBL22694965 | 0.80 | CYP1A2 (0.39) | CYP1A2MAPK1 | |
| SCHEMBL2399243 | 0.80 | TSHR (0.33) | — | |
| SCHEMBL806005 | 0.80 | — | — | |
| SCHEMBL22305533 | 0.78 | CYP1A2 (0.33) | CYP1A2MAPK1 | |
| Hydrochloric Acid SCHEMBL11597307 | 0.77 | CYP1A2 (0.43) | CYP1A2MAPK1CA12CA1CA2 | |
| SCHEMBL13501557 | 0.77 | PLA2G1B (0.34) | — | |
| SCHEMBL23457319 | 0.77 | PLA2G1B (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009618-A1 | BICYCLIC PGDH INHIBITORS AND METHODS OF MAKING AND USING | EPIRIUM BIO, INC. (US) | 2023-02-02 | — | — | WO | disclosed |