SCHEMBL24929013

SCHEMBL24929013

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc4c3oc3cccc(-c5ccc(-c6cccc7c6oc6ccccc67)c6sc7ccccc7c56)c34)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.39
PRKDC P78527 7/20 0.36
PIK3CD O00329 3/20 0.36
PIK3CB P42338 3/20 0.36
MAPT P10636 5/20 0.35
POLB P06746 2/20 0.35
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
NPSR1 Q6W5P4 1/20 0.34
TSHR P16473 3/20 0.34
LMNA P02545 2/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HPGD P15428 1/20 0.33
BRDT Q58F21 2/20 0.32
BRD4 O60885 1/20 0.32
PIK3CA P42336 1/20 0.32
MTOR P42345 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24929368 0.98 ALOX5 (0.39) ALOX5PRKDCPIK3CDPIK3CBMAPT
SCHEMBL26228694 0.97 ALOX5 (0.37) ALOX5PRKDCPIK3CDPIK3CBMAPT
SCHEMBL26214601 0.95 LIMK1 (0.36) PRKDCPIK3CDPIK3CBMAPTPOLB
SCHEMBL24929366 0.94 PRKDC (0.36) ALOX5PRKDCPIK3CDPIK3CBMAPT
SCHEMBL26215989 0.94 PRKDC (0.35) ALOX5PRKDCPIK3CDPIK3CBMAPT
SCHEMBL26216011 0.94 PRKDC (0.37) ALOX5PRKDCPIK3CDPIK3CBMAPT
SCHEMBL26214547 0.94 MAPT (0.35) ALOX5PRKDCPIK3CDPIK3CBMAPT
SCHEMBL24929501 0.93 ALOX5 (0.38) ALOX5PRKDCPIK3CDPIK3CBMAPT
SCHEMBL24929529 0.93 ALOX5 (0.38) ALOX5PRKDCPIK3CDPIK3CBMAPT
SCHEMBL24929393 0.93 BRDT (0.37) PRKDCPIK3CDPIK3CBMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023008795-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2023-02-02 WO disclosed