⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255843 | 1.00 | — | — | |
| SCHEMBL13302530 | 1.00 | — | — | |
| SCHEMBL14437434 | 0.97 | — | — | |
| SCHEMBL10431397 | 0.97 | MEN1 (0.46) | — | |
| SCHEMBL2660180 | 0.97 | — | — | |
| SCHEMBL22926500 | 0.97 | MEN1 (0.46) | — | |
| SCHEMBL4476204 | 0.92 | — | — | |
| SCHEMBL17887834 | 0.79 | — | — | |
| SCHEMBL10737278 | 0.79 | — | — | |
| SCHEMBL6263872 | 0.77 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113288899-B | Application of heterocyclic thiol compound in preparation of antitumor drugs | 浙江工业大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-113288899-A | Application of heterocyclic thiol compound in preparation of antitumor drugs | 浙江工业大学 | 2021-08-24 | — | — | CN | disclosed |
| US-9273333-B2 | Process for the preparation of intermediates of HMG-CoA reductase inhibitors | MYLAN LABORATORIES LTD (IN) | 2016-03-01 | — | — | US | disclosed |
| WO-2014195965-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF HMG-COA REDUCTASE INHIBITOR INTERMEDIATES | MYLAN LABORATORIES LTD (IN) | 2014-12-11 | — | — | WO | disclosed |
| US-20140349350-A1 | Novel Process for the Preparation of Intermediates of HMG-CoA Reductase Inhibitors | TIANISH LABORATORIES PRIVATE LIMITED (IN) | 2014-11-27 | — | — | US | disclosed |
| EP-2785851-A2 | PROCESS FOR PRODUCING CHIRAL STATIN SIDE CHAIN INTERMEDIATES EMPLOYING CANDIDA ANTARCTICA LIPASE B | Mylan Laboratories, Limited (IN) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013080219-A2 | NOVEL PROCESS FOR THE PREPARATION OF INTERMEDIATES OF HMG-CoA REDUCTASE INHIBITORS | MYLAN LABORATORIES LTD (IN) | 2013-06-06 | — | — | WO | disclosed |
| EP-2550257-A1 | PHARMACEUTICALLY ACTIVE DISUBSTITUTED TRIAZINE DERIVATIVES | Lead Discovery Center GmbH (DE) | 2013-01-30 | — | — | EP | disclosed |
| WO-2011116951-A1 | PHARMACEUTICALLY ACTIVE DISUBSTITUTED TRIAZINE DERIVATIVES | LEAD DISCOVERY CENTER GMBH (DE) | 2011-09-29 | — | — | WO | disclosed |
| US-7482481-B2 | Method for producing isocyanates | BASF AKTIENGESELLSCHAFT (DE) | 2009-01-27 | — | — | US | disclosed |
| US-7211689-B2 | Method for production of isocyanates | BASF AKTIENGESELLSCHAFT (DE) | 2007-05-01 | — | — | US | disclosed |
| US-7064233-B2 | Method for producing isocyanates | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-20 | — | — | US | disclosed |
| US-20040267047-A1 | Method for production of isocyanates | BASF AKTIENGESELLSCHAFT (DE) | 2004-12-30 | — | — | US | disclosed |
| US-20040260117-A1 | Method for producing isocyanates | BASF AKTIENGESELLSCHAFT (DE) | 2004-12-23 | — | — | US | disclosed |
| US-20040249193-A1 | Method for producing isocyanates | BASF AKTIENGESELLSCHAFT (DE) | 2004-12-09 | — | — | US | disclosed |
| US-4207334-A | Acylformamidine insecticidal and miticidal compounds | STAUFFER CHEMICAL COMPANY (US) | 1980-06-10 | — | — | US | disclosed |
| US-4130662-A | Acylformanidine insecticidal and miticidal compounds | STAUFFER CHEMICAL COMPANY (US) | 1978-12-19 | — | — | US | disclosed |
| US-4056570-A | Acylformanidine insecticidal and miticidal compounds | STAUFFER CHEMICAL COMPANY (US) | 1977-11-01 | — | — | US | disclosed |
| US-3962305-A | INSECTICIDES, MITICIDES | STAUFFER CHEMICAL COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3857836-A | HERBICIDAL AGENTS | HOECHST AG | 1974-12-31 | — | — | US | disclosed |