SCHEMBL4255843

SCHEMBL4255843

CCCCC/N=C\N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13302530 1.00
SCHEMBL2492904 1.00
SCHEMBL14437434 0.97
SCHEMBL10431397 0.97 MEN1 (0.46)
SCHEMBL2660180 0.97
SCHEMBL22926500 0.97 MEN1 (0.46)
SCHEMBL4476204 0.92
SCHEMBL17887834 0.79
SCHEMBL10737278 0.79
SCHEMBL6263872 0.77 TSHR (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024148149-A2 COMPOSITIONS AND METHODS FOR CONTROLLING GLUCOSE LEVELS SIRTSEI PHARMACEUTICALS, INC. (US) 2024-07-11 WO disclosed
WO-2024059705-A1 COMPOSITIONS AND METHODS FOR TREATING DEPRESSION IN FEMALES SIRTSEI PHARMACEUTICALS, INC. (US) 2024-03-21 WO disclosed
US-7482481-B2 Method for producing isocyanates BASF AKTIENGESELLSCHAFT (DE) 2009-01-27 US disclosed
US-7211689-B2 Method for production of isocyanates BASF AKTIENGESELLSCHAFT (DE) 2007-05-01 US disclosed
US-7064233-B2 Method for producing isocyanates BASF AKTIENGESELLSCHAFT (DE) 2006-06-20 US disclosed
US-20040267047-A1 Method for production of isocyanates BASF AKTIENGESELLSCHAFT (DE) 2004-12-30 US disclosed
US-20040260117-A1 Method for producing isocyanates BASF AKTIENGESELLSCHAFT (DE) 2004-12-23 US disclosed
US-20040249193-A1 Method for producing isocyanates BASF AKTIENGESELLSCHAFT (DE) 2004-12-09 US disclosed