SCHEMBL24929357

SCHEMBL24929357

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)sc3cccc(-c5ccc(-c6cccc7c6sc6ccccc67)c6c5oc5ccccc56)c34)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.37
PRKDC P78527 8/20 0.37
PIK3CD O00329 2/20 0.37
PIK3CB P42338 2/20 0.37
BRDT Q58F21 2/20 0.36
BRD4 O60885 1/20 0.36
PIK3CA P42336 1/20 0.36
MTOR P42345 1/20 0.36
PIK3CG P48736 1/20 0.36
KCNH2 Q12809 1/20 0.36
MAPT P10636 3/20 0.32
POLB P06746 2/20 0.32
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
PARP14 Q460N5 1/20 0.31
ESR2 Q92731 1/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24929037 0.94 ALOX5 (0.38) ALOX5PRKDCPIK3CDPIK3CBBRDT
SCHEMBL23822663 0.94 ALOX5 (0.38) ALOX5PRKDCPIK3CDPIK3CBBRDT
SCHEMBL24929363 0.94 BRDT (0.39) ALOX5BRDTMAPTPOLBTSHR
SCHEMBL23349814 0.92 ALOX5 (0.38) ALOX5PRKDCPIK3CDPIK3CBBRDT
SCHEMBL24929388 0.92 BRDT (0.37) ALOX5BRDTMAPTPOLBTSHR
SCHEMBL23349552 0.92 PRKDC (0.38) ALOX5PRKDCPIK3CDPIK3CBBRDT
SCHEMBL23349807 0.92 PRKDC (0.36) ALOX5PRKDCPIK3CDPIK3CBBRDT
SCHEMBL23349855 0.92 BRDT (0.37) ALOX5PRKDCPIK3CDPIK3CBBRDT
SCHEMBL23349813 0.91 PRKDC (0.41) ALOX5PRKDCPIK3CDPIK3CBBRDT
SCHEMBL24929552 0.91 PRKDC (0.41) ALOX5PRKDCPIK3CDPIK3CBBRDT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023008795-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2023-02-02 WO disclosed