SCHEMBL24929423

SCHEMBL24929423

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc4c3sc3ccc(-c5ccc(-c6cccc7c6oc6ccccc67)c6oc7ccccc7c56)cc34)n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.41
GGPS1 O95749 1/20 0.34
PRKDC P78527 8/20 0.34
PIK3CD O00329 3/20 0.34
PIK3CB P42338 3/20 0.34
BRD4 O60885 1/20 0.33
PIK3CA P42336 1/20 0.33
MTOR P42345 1/20 0.33
PIK3CG P48736 1/20 0.33
KCNH2 Q12809 1/20 0.33
BRDT Q58F21 1/20 0.33
PTGES2 Q9H7Z7 1/20 0.32
MAPT P10636 2/20 0.32
PIM1 P11309 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
PIM3 Q86V86 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
ALDH1A1 P00352 2/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24929419 0.97 ALOX5 (0.42) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL24929659 0.94 ALOX5 (0.41) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL26240723 0.94 ALOX5 (0.37) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL26240687 0.94 ALOX5 (0.37) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL24929611 0.93 ALOX5 (0.39) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL26219821 0.93 ALOX5 (0.37) ALOX5PRKDCPIK3CDPIK3CBMAPT
SCHEMBL26226315 0.93 ALOX5 (0.37) ALOX5PRKDCPIK3CDPIK3CBMAPT
SCHEMBL26763085 0.93 ALOX5 (0.37) ALOX5PRKDCPIK3CDPIK3CBMAPT
SCHEMBL24217373 0.93 ALOX5 (0.47) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL23349535 0.92 ALOX5 (0.43) ALOX5GGPS1PRKDCPIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023008795-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2023-02-02 WO disclosed